It is fitting that the first book devoted exclusively to renal transplantation should have come from the gifted pen of the British surgeon, Roy Calne. This young Englishman, working with Dr. Joseph E. Murray, changed the course of clinical transplantation endeavor with his disclosures concerning the immuno-suppressive properties of some thiopurine derivatives and other pharmacological agents. The events in this magnificent laboratory achievement, related humbly and with equal emphasis on success and failure, form the central portion of the work. Nevertheless, other aspects of accomplishment in this field are fully and succinctly covered. Historical development, surgical techniques, consideration of mechanisms of rejection, issues of morality applying to this kind of surgery, and the role of living versus cadaveric donation are all described.
In essence, the book is a well-documented collection of virtually all pertinent information bearing directly or indirectly on renal homotransplantation to early 1962. It is a tribute to