We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Other Articles |

The Genetics of Schizophrenia: A Study of Heredity and Reproduction in the Families of 1,087 Schizophrenics

JAMA. 1940;114(26):2591-2592. doi:10.1001/jama.1940.02810260077036.
Text Size: A A A
Published online


This book presents the results of a study of 1,087 schizophrenic probands and their families. The material, obtained in a German population, by painstaking investigation of schizophrenic patients in the Herzberge Hospital of Berlin between 1893 and 1902, although unselected, was rigorously classified. All blood relations were exhaustively surveyed and discriminately diagnosed. Statistical, classificatory, demographic and social analysis yielded figures for fertility, mortality, disease expectancy and genetic data.

The author, in his foreword, states that the principal aim of the investigations was to offer conclusive proof of the inheritance of schizophrenia and to establish a dependable basis for the clinical and eugenic activities of psychiatry. Analysis of the data reveals hereditoconstitutional factors having a decisive influence in the origin of schizophrenia, as the following conclusions indicate:

  1. Families affected by schizophrenia show a progressive and uninterrupted social decline.

  2. Germinally affected and overt schizophrenic individuals show a lowered marriage and


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.