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Der tuberkulös überempfindliche Mensch

JAMA. 1940;114(15):1488. doi:10.1001/jama.1940.02810150074036.
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ABSTRACT

Tuberculosis may be considered an infectious disease and an allergic disease. The former requires the determination of tubercle bacilli for diagnosis and the tuberculous tissue characterized by tubercle. It is known that tuberculosis begins mostly as a primary complex in the lungs, but there is a form of tuberculosis with no determinable primary complex; no tubercle bacilli can be found, but only inflammatory changes are discernible. "Allergy," as known in tuberculosis since Pirquet and described in detail in pulmonary tuberculosis by Ranke, is not being dealt with by the author. "Allergy" to Pirquet meant a "changed reaction ability" of the body. With added information, this has been extended so that it includes the anaphylactic changes. Now the extended allergy is intended to mean the inclusion of an anaphylaxis—a hyperallergy. We know that the tubercle bacillus not only possesses a very high resistance to all contacting influences but exerts a very

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