0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Other Articles |

THE USE OF VITAMIN B6 IN PSEUDOHYPERTROPHIC MUSCULAR DYSTROPHY

WILLIAM ANTOPOL, M.D.; CLEMENT E. SCHOTLAND, M.D.
JAMA. 1940;114(12):1058-1059. doi:10.1001/jama.1940.02810120030007.
Text Size: A A A
Published online

The finding of foci of muscle atrophy in vitamin B6 deficient rats1 and the production of tremors and convulsions in rats after the administration of massive doses of synthetic vitamin B62 indicated that vitamin B6 might have some effect on muscle action. Accordingly it was decided to determine whether 2-methyl3-hydroxy-4,5-dihydroxy methyl pyridine (vitamin B6) had any effect on the muscular dystrophies of man. This communication deals with six cases of pseudohypertrophic muscular dystrophy which were treated with the synthetic vitamin.

REPORT OF CASES 

Case 1.—  A boy was first seen in February 1938 at the age of 4. For one year prior to this time his mother noted that he was reluctant to walk, walked unsteadily requiring a wide base, fatigued easily on walking and had difficulty in rising from a supine position. In January 1939 he had to pull himself upstairs by sheer

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();