0
Other Articles |

DELAYED CUTANEOUS REACTION TO INTRADERMAL INJECTION OF BRUCELLERGEN IN BRUCELLOSIS

L. E. January, M.D.; James A. Greene, M.D.
JAMA. 1940;114(6):486-487. doi:10.1001/jama.1940.62810060001008.
Text Size: A A A
Published online

The cutaneous reaction following the intradermal injection of brucellergen is one of the diagnostic aids in brucellosis. The reaction, when positive, begins within twenty-four to thirty-six hours after injection and persists for more than forty-eight hours. The test is positive if, in addition to an area of erythema around the site of injection, there is also edema or induration which measures from 0.5 to 0.75 cm. or more in diameter. A delayed reaction, that is, one which does not begin until forty-eight hours or more after injection, is rare. It is for this reason that we are reporting a case in which the cutaneous reaction did not appear until the fourth day after the injection of brucellergen.

REPORT OF CASE  A farmer aged 43 entered the University Hospital July 10, 1938, because of headache, pain in the legs and fever. He had always enjoyed good health until December 1937, when

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();