COMPLETE ANURIA DUE TO CRYSTALLINE CONCRETIONS FOLLOWING THE USE OF SULFAPYRIDINE IN PNEUMONIA

Sulfapyridine is being so widely used, it is imperative that physicians have knowledge of the possible complications which may occur during its administration. We are reporting a most instructive case which clinically bears out in all details the animal experiments reported by Antopol and Robinson¹ Gross, Cooper and Lewis² and the unpublished work of Lloyd R. Jones, professor of bacteriology at St. Louis University. All the investigators report the presence of concretions in the urinary tracts of animals within forty-eight hours after administration

Tsao³ reports a number of cases of hematuria following the use of sulfapyridine and ascribes the death of a child to crystalline concretions forming at the ureterovesical orifices which completely blocked the ureters and resulted in anuria which caused the death of the patient. He states that a urologist's assistance may have prevented the death of the child.

REPORT OF CASE  R. W., a