0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Other Articles |

THE PRESENT STATUS OF LIPOCAIC

LESTER R. DRAGSTEDT, Ph.D., M.D.
JAMA. 1940;114(1):29-32. doi:10.1001/jama.1940.02810010031007.
Text Size: A A A
Published online

The probability that the pancreas furnishes more than one internal secretion to the organism was suggested by the discovery of more than one type of cell in the islets of Langerhans. The evidence that insulin is elaborated by the beta cells of the islets is now fairly conclusive. The function of the alpha cells remains unknown. In 1924 Fisher1 and Allan, Bowie, Macleod and Robinson2 demonstrated that completely depancreatized dogs could not be maintained alive for long even though adequately treated with insulin. At death the most obvious change observed was an extensive fatty infiltration and degeneration in the liver. In one experiment, however, Fisher noted an extreme degree of arteriosclerosis of the aorta. The addition of raw pancreas to the diet was found by Macleod and his associates to prevent the development of these changes in the liver and to permit survival for long periods of time.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();