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November 25, 1939, Vol 113, No. 22 >
Other Articles | November 25, 1939

VULVOVAGINITIS IN PREGNANCY

Edward G. Waters, M.D.; Eakle W. Cartwright, M.D.
JAMA. 1939;113(22):1982. doi:10.1001/jama.1939.02800470058024.
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ABSTRACT

To the Editor:—  We submit a few comments subsequent to those of Dr. H. Close Hesseltine with respect to our article "The Significance of Vulvovaginitis in Pregnancy" published in The Journal July 1, 1939, page 30.All patients with symptoms and/or vaginal discharge had both the direct Sabouraud and the culture-transfer technic employed. The latter seemed to give a higher incidence of positive results and the incidence we reported was as we found it. Observations by one of us (E. G. W.) on 1,500 private patients shows a much lower clinical incidence.The words "type of" should have preceded "lochial flow" in ascribing the postpartum disappearance of Monilia to the alteration in vaginal function. In our comment it is suggested that hyperestrinism with sequential vaginal changes in pregnancy may account for the appearance of Monilia in certain pregnant women. Inversely the rapid fall in estrogen results in glycogen-poor vaginal secretion

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