Other Articles |


JAMA. 1936;107(15):1208-1212. doi:10.1001/jama.1936.02770410030007.
Text Size: A A A
Published online

For the past few years in the neurologic service at Bellevue Hospital, under the direction of Dr. Foster Kennedy, we have been studying the etiology and treatment of migraine. Realizing that this affliction is not a disease entity and that there is more than one precipitating factor in the production of this syndrome, we felt it essential to investigate this paradox from many different angles.

In a report in 1934 we1 approached the problem from a pharmacologic point of view. At that time we administered known vasodilator and vasoconstrictor agents, also glandular products such as pitressin, extract of anterior pituitary, theelin and insulin. We also studied the effects of carbon dioxide inhalation, of vagomimetic and of sympathomimetic compounds on the attacks. These various medications were used in order to compare the relative effectiveness of numerous nonsedative measures in relieving the episode, as well as to determine the factors capable


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.