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MULTIPLE SYMMETRICAL LIPOMATOSIS

J. K. Miller, M.D.
JAMA. 1936;106(24):2059-2060. doi:10.1001/jama.1936.92770240001009.
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Lipomas may occur anywhere within the body and have been found in the cranial cavity, the mediastinum, the uterus and the marrow cavity of the bones. Because of their wide distribution they have been classified as subcutaneous, intermuscular and visceral. The majority are located under the skin and occur most frequently on the trunk, thighs and arms. The face, scalp, sternal region, hands and lower legs are infrequent sites.

Pack and LeFevre,1 in a study of 19,129 tumor cases, of which 2,564 were benign growths, found that lipomas included 4.3 per cent of all benign tumors. Adair,2 reporting the regional distribution of 352 lipomas in 134 patients, had a frequency of from 4 to 5 per cent of all benign tumors. Of these, nine cases (6.7 per cent) were multiple lipomas. Adair included a case presenting 160 distinct tumors. Of the 352

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