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CLINICAL STUDY UNDER CONTROLLED CONDITIONS OF 1,083 CHILDREN WITH HOOKWORM

A. E. KELLER, M.D.; J. T. GOOGE, M.D., C.P.H.; H. B. COTTRELL, M.D., C.P.H.; D. G. MILLER Jr., M.D.; R. H. HARVEY, M.D.
JAMA. 1935;105(21):1670-1675. doi:10.1001/jama.1935.02760470024006.
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A recent investigation1 of the hookworm problem in Mississippi revealed that there had occurred a marked decrease in both incidence and intensity of hookworm infestation since 1914. No recent clinical studies of hookworm have been made to determine its effects on the health of school children under these conditions of lowered prevalence and intensity of infestation. Since methods are now available by which with a fair degree of accuracy the physical condition of the patient can be studied in relation to the hookworm burden, the present report deals with such a study among rural school children in George County, located in southeastern Mississippi.

This particular area was studied because it was known that 40.8 per cent of 1,618 white persons were found in that county to have hookworm during the recent state-wide study in Mississippi. Since it has been established that the highest incidence and intensity of infestation of

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