The preparation of this edition has been the sole responsibility of H. P. Fairlie. Anesthetic agents and methods of their administration that are in general use in Great Britain are described. The equipment used differs considerably from the equipment commonly in use in the United States and Canada and should be interesting to members of the profession in this country on that account. Stress is laid in the first chapters on the fundamentals underlying the absorption and physiologic action of anesthetic drugs. Shock in relation to anesthesia is adequately discussed in chapter 2. In chapter 7 the newer basal narcotics tribrom-ethanol (Avertin) and evipan sodium are described. Ether is recognized as the most dependable and safest anesthetic agent for the majority of operative procedures. The dangers associated with administration of chloroform are well outlined. The importance of maintaining an adequate airway during administration of an anesthetic by inhalation is stressed.