JAMA. 1935;105(5):327-331. doi:10.1001/jama.1935.02760310001001.
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Most of us are probably agreed that the therapeutic problem of acne is not yet satisfactorily solved. The early favorable results with roentgen therapy and especially the wider use of this modality following the more exact dosage obtainable with the Coolidge tube made it seem for some years that little more was needed, but a later appraisal of the results seems to have shown that there is still room for improvement. This realization together with the more recent knowledge of female hormone physiology and therapy has led to a renewed interest in the therapeutic problem of the disease. At present there is a state of flux concerning it. Formerly the treatment was practically routinized, the routine being so many doses of the roentgen ray. Now there is a greater tendency to recognize the limitations of the therapeutic weapons and to individualize and select treatment according to each case. To me


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