Quitting smoking (smoking cessation) is one of the most important things you can do to improve your health and well-being. People who stop smoking decrease their risk of cancer, heart disease, stroke, and early death. Women who stop smoking before or during pregnancy reduce their risk of infertility or having a low-birth-weight baby. Most smokers in the United States report that they want to stop smoking, but kicking the smoking habit can be difficult. Most ex-smokers try several times, often as many as 8 to 10 times, before they are able to quit for good. The results are definitely worth those efforts. The December 8, 2010, issue of JAMA includes a study reporting that smoking cessation treatment can be successfully combined with treatment for posttraumatic stress disorder. This Patient Page is based on one previously published in the December 12, 2007, issue of JAMA.