0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Letters |

Risk of Invasive Streptococcal Disease

William H. Wiese, MD
JAMA. 1998;280(21):1828. doi:10-1001/pubs.JAMA-ISSN-0098-7484-280-21-jbk1202.
Text Size: A A A
Published online

Extract

To the Editor.—In its analysis of the risk of invasive group A streptococcal infection among household contacts of case patients, the Working Group on Prevention of Invasive Group A Streptococcal Infections1 used data derived from surveillance conducted in Ontario to conclude that the rate of infection in household contacts exceeds the overall rate in the population by almost 200-fold. This computation is based on comparing the incidence of cases among contacts with the annual incidence in Ontario. The observation period for incidence among contacts, however, is only 1 month. To compute the relative risk for the contacts, the background incidence likewise should be expressed as a monthly incidence. If this is done by dividing the annual rate by 12, the rates per month are 294 cases per 100,000 contacts and 0.125 case per 100,000 in the overall population. Recalculating excess risk with these rates, the excess risk in household contacts is more than 2300-fold. This approach to calculation does not take into account effects of seasonal clustering of cases. Nevertheless, it should provide a more realistic estimate of increased risk than the approach used by the Working Group.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();