Author Contributions: Dr Pilote had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Avgil Tsadok, Jackevicius, Humphries, Pilote.
Acquisition of data: Avgil Tsadok, Behlouli, Pilote.
Analysis and interpretation of data: Avgil Tsadok, Jackevicius, Rahme, Pilote.
Drafting of the manuscript: Avgil Tsadok, Rahme, Pilote.
Critical revision of the manuscript for important intellectual content: Avgil Tsadok, Jackevicius, Humphries, Behlouli, Pilote.
Statistical analysis: Avgil Tsadok, Rahme, Behlouli.
Obtained funding: Jackevicius, Pilote.
Administrative, technical, or material support: Avgil Tsadok.
Study supervision: Jackevicius, Pilote.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Avgil Tsadok reported receiving a fellowship award from the Canadian Institutes of Health Research (CIHR) and receiving a travel award from the CIHR to present the study results at a conference (American Heart Association 2011 Scientific Sessions). Dr Humphries reported receiving a new investigator award from the CIHR. Dr Pilote reported serving as a James McGill Chair at McGill University and receiving a national investigator award from the Fonds de recherche en santé du Québec.
Funding/Support: This study was supported by operating grant MOP-84304 from the CIHR.
Role of the Sponsor: The CIHR had no role in the design and conduct of the study; the collection, analysis, and interpretation of the data; or the preparation, review, or approval of the manuscript.