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Editorial |

Toward More Accurate Detection and Risk Stratification of Chronic Kidney Disease

Kamyar Kalantar-Zadeh, MD, MPH, PhD; Alpesh N. Amin, MD, MBA
JAMA. 2012;307(18):1976-1977. doi:10.1001/jama.2012.4623.
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The term chronic kidney disease (CKD) was first proposed and systematically defined in 2002, and the 5 incremental stages for the degree of severity of CKD were described based on the estimated glomerular filtration rate (GFR) (stage 1, ≥90; stage 2, 60-89; stage 3, 30-59; stage 4, 15-29; and stage 5, <15 mL/min/1.73 m2). Stage 1 is the least severe and stage 5 is classified as kidney failure.1,2 The estimated GFR (calculated from the Modification of Diet in Renal Disease [MDRD] Study equation)3 can be derived automatically from a single serum creatinine measurement, combined with the easily available age and sex data, plus a qualifying statement on race, and without a need for patient weight.

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