Author Contributions: Dr B Smith had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: G. Smith, Xu, Buchholz, Shih, B. Smith.
Acquisition of data: G. Smith, Giordano, B. Smith.
Analysis and interpretation of data: G. Smith, Xu, Giordano, Jiang, Shih, B. Smith.
Drafting of the manuscript’ s. Smith, Buchholz, B. Smith.
Critical revision of the manuscript for important intellectual content: G. Smith, Xu, Giordano, Shih, B. Smith.
Statistical analysis: G. Smith,, Xu, Jiang, Shih, B. Smith.
Obtained funding: G. Smith, Giordano, B. Smith.
Administrative, technical, or material support: G. Smith, Giordano, B. Smith.
Study supervision: G. Smith, B. Smith.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Smith receives research support from Varian Medical Systems, but this support was not used for any portion of the current manuscript. None of the other coauthors have conflicts to report.
Funding/Support: Dr B. Smith and Dr Giordano are supported by grant RP101207 from the Cancer Prevention & Research Institute of Texas. Dr G. Smith was supported by a Multidisciplinary Postdoctoral Award from the Department of Defense. Dr Shih is supported by grant R01 HS018535 from the Agency for Healthcare Research and Quality and by grants RC1CA145799 and R21CA165092 from the National Cancer Institute, and from the University of Chicago Cancer Research Foundation Women's Board. This study was also supported in part by grants CA16672 and T32CA77050 from the Department of Health and Human Services National Cancer Institute. This study was also supported by a philanthropic gift from Ann Cazalot and Clarence Cazalot.
Role of the Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Online-Only Material: The Author Video Interview is available here.
Online-Only Material: The Author Audio Interview is available here.
Additional Contributions: The authors would like to thank Yu Shen, PhD, Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center for her statistical advice regarding this manuscript, for which he received no compensation.