Author Contributions: Dr Auer had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Auer, Newman, Rodondi.
Acquisition of data: Auer, Bauer, Satterfield, Newman, Rodondi.
Analysis and interpretation of data: Auer, Bauer, Marques-Vidal, Butler, Min, Cornuz, Satterfield, Vittinghoff, Rodondi.
Drafting of the manuscript: Auer, Marques-Vidal, Butler.
Critical revision of the manuscript for important intellectual content: Auer, Bauer, Butler, Min, Cornuz, Satterfield, Newman, Vittinghoff, Rodondi.
Statistical analysis: Auer, Marques-Vidal, Butler, Vittinghoff, Rodondi.
Obtained funding: Auer, Newman, Rodondi.
Administrative, technical, or material support: Satterfield, Newman, Rodondi.
Study supervision: Bauer, Butler, Rodondi.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Bauer reported receiving grants from Novartis and Amgen. Dr Butler reported receiving research support from National Institutes of Health, Amgen, Medtronic, GE Healthcare, and Boston Scientific; and being a consultant to Bayer, Cardiomems, Trevena, Takeda, Ono Pharmaceutical, and Events Committee Corthera and World Heart. Dr Satterfield reported receiving a grant contract for Health ABC Study from the National Institute on Aging. Dr Vittinghoff reported receiving a grant for support as consulting statistician for training program from the National Institutes of Health. No other authors reported any disclosures.
Health ABC Study Principal Investigators and Coordinators: Anne B. Newman, MD, MPH, Piera Kost, Diane Ives, University of Pittsburgh, Pittsburgh; Suzanne Satterfield, MD, DrPH, Frances A. Tylavsky, DrPH, Jan Elam, University of Tennessee, Memphis; Stephen B. Kritchevsky, PhD, Wake Forest University, Winston-Salem, North Carolina; Steven R. Cummings, MD, Michael C. Nevitt, PhD, Susan M. Rubin, MPH, University of California, San Francisco; Tamara B. Harris, MD, Melissa E. Garcia, MPH, National Institute on Aging, Bethesda, Maryland.
Funding/Support: This work was supported by grants N01-AG-6-2101, N01-AG-6-2103, and N01-AG-6-2106 from the National Institute on Aging (NIA), National Institutes of Health (NIH); grant R01-AG028050 from the NIA, grant R01-R012459 from the National Institute of Nursing Research, and in part by the Intramural Research Program of the NIH, NIA. The NIA funded the Health ABC Study, reviewed the manuscript, and approved its publication. Dr Auer's research on cardiovascular prevention is supported by grants SPUM 33CM30-124112 and PBLAP3-136774 from the Swiss National Science Foundation and the Swiss Heart Foundation.
Role of the Sponsors: The funding organizations had no role in the design and conduct of the study, in the collection, management, analysis, and interpretation of the data, or in the preparation of the manuscript. Before submission for publication, the manuscript was reviewed and approved by the NIA.
Additional Contributions: We thank the other investigators, staff, and the participants of the Health ABC Study for their valuable contributions.