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Letters |

Cardiovascular Events in Adults Taking Medications for ADHD—Reply

Laurel A. Habel, PhD; Bruce Fireman, MS; William O. Cooper, MD, MPH
JAMA. 2012;307(14):1485-1486. doi:10.1001/jama.2012.449.
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In Reply: We acknowledge that our study had limited ability to examine the risk of cardiovascular events associated with long-term use of ADHD medications. Yet our data suggest that most adult use of ADHD medications is relatively short-term. Among the approximately 50% of our study cohort who were new users at cohort entry, 75% had less than 8 months of use; 75% of the prevalent users had less than 15 months of use during follow-up. Nonetheless, some of the prevalent users may have taken ADHD medications for several years. In subgroup analyses, we did not find any evidence of elevated risk among the prevalent users.

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April 11, 2012
John J. Devlin, MD; Mohan Punja, MD; Ziad N. Kazzi, MD
JAMA. 2012;307(14):1485-1486. doi:10.1001/jama.2012.448.
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