Author Contributions: Dr Floyd had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Floyd, Heckbert, Psaty.
Acquisition of data: Floyd, Heckbert, Carrell, Psaty.
Analysis and interpretation of data: Floyd, Heckbert, Weiss, Psaty.
Drafting of the manuscript: Floyd, Psaty.
Critical revision of the manuscript for important intellectual content: Floyd, Heckbert, Weiss, Carrell, Psaty.
Statistical analysis: Floyd.
Obtained funding: Psaty.
Administrative, technical, or material support: Carrell, Psaty.
Study supervision: Heckbert, Weiss, Psaty.
Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Psaty reported serving on a data and safety monitoring board for the clinical trial of a device funded by Zoll and serving on a steering committee for the Yale Open Data Access Project funded by Medtronic. No other authors reported disclosures.
Funding/Support: This research was supported in part by grants HL078888 and HL085251 from the National Heart, Lung, and Blood Institute. Dr Floyd was supported by National Heart, Lung, and Blood Institute training grant T32 HL007902. Dr Carrell was supported by grant U01 HG006375 from the National Human Genome Research Institute.
Role of the Sponsors: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.