Defined broadly, a biomarker is a physiological variable that can be measured objectively and reliably1 and connotes some biological characteristic about the patient in whom it is measured. As such, biomarkers either can be used as a surrogate for a hard end point, correlating with an important clinical outcome of interest, or can be used to provide prognostic information—predictive of future events and, at their best, a tool to influence treatment strategies. In this commentary, we argue that this latter use is the most appropriate application for biomarkers.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 6
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.