Author Contributions: Drs Sorror and Storer had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Sorror, Sandmaier, Maris, Mielcarek, Niederwieser, Storb.
Acquisition of data: Sorror, Sandmaier, Franke, Chauncey, Agura, Langston, Hari, Pulsipher, Bethge, Sahebi, Bruno, Maris, Yeager, Petersen, Vindeløv, McSweeney, Hübel, Mielcarek, Georges, Blume, Maloney.
Analysis and interpretation of data: Sorror, Sandmaier, Storer, Laport, Chauncey, Maziarz, Pulsipher, Bethge, Sahebi, Maris, Yeager, Hübel, Mielcarek, Georges, Maloney, Storb.
Drafting of the manuscript: Sorror, Laport, Sahebi, Storb.
Critical revision of the manuscript for important intellectual content: Sorror, Sandmaier, Storer, Franke, Chauncey, Agura, Maziarz, Langston, Hari, Pulsipher, Bethge, Bruno, Maris, Yeager, Petersen, Vindeløv, McSweeney, Hübel, Mielcarek, Georges, Niederwieser, Blume, Maloney, Storb.
Statistical analysis: Storer, Bethge.
Obtained funding: Sorror, Sandmaier, Petersen, Maloney, Storb.
Administrative, technical, or material support: Chauncey, Hari, Pulsipher, Bethge, Sahebi, Petersen, Hübel, Mielcarek, Blume, Storb.
Study supervision: Sandmaier, Laport, Agura, Hari, Maris, McSweeney, Georges, Maloney, Storb.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Sandmaier reported serving on the board of ArevaMed. Dr Franke reported receiving travel/accommodations/meeting expenses for the European Group of Blood and Marrow Transplantation 2009 meeting. Dr Maziarz reported receiving grants or grants pending (grant money to institution) from Japanese Heath Sciences, Athersys Inc, and BMT/CTN; serving on the speakers bureaus of Millennium Pharmaceuticals Inc and Genzyme Inc; receiving royalties from Springer for publication of a book; and receiving honoraria for lectures (groups change yearly; usually related to community oncology educational efforts). Dr Bethge reported serving as a consultant for Miltenyi Biotech GmbH; receiving grants or grants pending from Medac GmbH, Fresenius GmbH, Pfizer, and Miltenyi Biotech GmbH; receiving payment for lectures from Miltenyi Biotech GmbH; and receiving travel/accommodations/meeting expenses from Medac GmbH. Dr Sahebi reported receiving travel/accommodations/meeting expenses and a research fund from Millennium Pharmaceuticals. Dr Vindeløv reported receiving research grants from the Danish Cancer Society, The Lundbeck Foundation, and the Research Council of Rigshospitalet and receiving a travel and research grant from the Region of the Capital of Denmark. No other authors reported disclosures.
Funding/Support: Research for this study has been supported by grants from the National Institutes of Health (NIH) (P01HL036444, P01CA078902, P01CA018029, P30CA015704, and R00HL088021) and from the Leukemia/Lymphoma Society (7008-08).
Role of the Sponsor: Neither the NIH nor the Leukemia/Lymphoma Society had any role in the design or conduct of the study; the collection, management, analysis, or interpretation of the data; or the preparation, review, or approval of the manuscript.
Disclaimer: The views expressed in this article are solely the responsibility of the authors and do not necessarily represent the official views of the NIH or its subsidiary institutes and centers.
Additional Contributions: We are grateful to all research nurses and data coordinators for implementation of protocols. We also thank our administrative staff for their assistance with manuscript preparation. We are grateful to the many physicians, nurses, physician assistants, nurse practitioners, pharmacists, and support staff who cared for our patients, and to the patients who allowed us to care for them and who participated in our ongoing clinical research.