Author Contributions: Dr Antoniucci had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Parodi, Abbate, Antoniucci.
Acquisition of data: Marcucci, Gori, Giusti, Buonamici.
Analysis and interpretation of data: Valenti, Migliorini, Gensini, Antoniucci.
Drafting of the manuscript: Antoniucci.
Critical revision of the manuscript for important intellectual content: Parodi, Marcucci, Valenti, Gori, Migliorini, Giusti, Buonamici, Gensini, Abbate.
Statistical analysis: Valenti.
Obtained funding: Antoniucci.
Study supervision: Parodi.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Parodi reported receiving consulting fees from Daiichi Sankyo/Eli Lilly. Dr Marcucci reported receiving honoraria for lectures from Daiichi Sankyo/Eli Lilly and Merck Sharp & Dohme. Dr Gensini reported receiving consulting fees from Bayer, Boehringer Ingelheim, and Eli Lilly; lecture fees from AstraZeneca, GlaxoSmithKline, Instrumentation Laboratory, Menarini, and Sigma Tau; and research grant funding from Novo Nordisk, Merck Sharp & Dohme, Pfizer, Pierrel, sanofi-aventis, and Servier. Dr Abbate reported receiving consulting fees from Eli Lilly; lecture fees from Instrumentation Laboratory and Sigma Tau; and research grant funding from Bayer, Boehringer Ingelheim, and Pfizer. Dr Antoniucci reported receiving consulting fees from Daiichi Sankyo/Eli Lilly and The Medicines Company and serving on the advisory boards of Cordis and CID. No other disclosures were reported.
Funding/Support: This study was supported by an unrestricted grant from the Italian Health Ministry to the Tuscany Region for the Finalized Medical Research Program 2007.
Role of the Sponsor: The study sponsor had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Previous Presentation: This study was presented in part at EuroPCR; May 17, 2011; Paris, France.