Author Contributions: Dr Franklin had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Franklin, Freeman, Compton, Moore, Garcia, Foa, March.
Acquisition of data: Franklin, Sapyta, Freeman, Khanna, Moore, Choate-Summers, Garcia, March.
Analysis and interpretation of data: Franklin, Sapyta, Khanna, Compton, Almirall, Edson, March.
Drafting of the manuscript: Franklin, Sapyta, Khanna, Almirall, Edson, March.
Critical revision of the manuscript for important intellectual content: Franklin, Sapyta, Freeman, Khanna, Compton, Almirall, Moore, Choate-Summers, Garcia, Edson, Foa, March.
Statistical analysis: Sapyta, Compton, Almirall, March.
Obtained funding: Franklin, Freeman, Garcia, Foa, March.
Administrative, technical, or material support: Franklin, Sapyta, Freeman, Khanna, Moore, Choate-Summers, Garcia, Edson, Foa, March.
Study supervision: Franklin, Sapyta, Freeman, Khanna, Choate-Summers, March.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr March has received speaker fees from Pfizer, consulting fees from Pfizer and Wyeth, and research support from Pfizer and Lilly, and has served as a scientific advisor for Pfizer and on the data and safety monitoring board for Organon, AstraZeneca, and Pfizer. Ms Edson and Drs Franklin, Sapyta, Freeman, Khanna, Compton, Almirall, Moore, Choate-Summers, Garcia and Foa did not report any financial conflicts of interest.
POTS Team: Primary investigators: Martin Franklin (Penn), Jennifer Freeman, Henrietta Leonard (Brown), John March (Duke). Coinvestigators: Penn: Muniya Khanna, Edna Foa; Brown: Abbe Garcia; Duke: Jeffrey Sapyta, Phoebe Moore, Allan Chrisman, David Fitzgerald.
Funding/Support: The Pediatric OCD Treatment Study II was supported by grants 2R01MH055126-08A2 (Penn), 2R01MH055121-06A2 (Duke), and 1R01MH064188-01A2 (Brown) from the National Institute of Mental Health.
Role of the Sponsor: The study sponsor had no role in the design and conduct of the study; in the collection, management, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Online-Only Material: The author interview is available here.