Author Contributions: Dr Yaffe had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Yaffe, Redline, Spira, Ancoli-Israel, Stone.
Acquisition of data: Redline, Ensrud.
Analysis and interpretation of data: Yaffe, Laffan, Harrison, Redline, Ancoli-Israel, Stone.
Drafting of the manuscript: Yaffe, Laffan, Harrison, Redline.
Critical revision of the manuscript for important intellectual content: Laffan, Redline, Spira, Ensrud, Ancoli-Israel, Stone.
Statistical analysis: Laffan, Harrison, Ancoli-Israel, Stone.
Obtained funding: Yaffe, Redline, Ensrud, Ancoli-Israel, Stone.
Administrative, technical, or material support: Yaffe, Laffan, Redline.
Study supervision: Yaffe, Stone.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Yaffe reported that she is a consultant for Novartis Inc; serves on data and safety monitoring boards for Pfizer, Medivation, and the National Institute of Mental Health; is a board member for Beeson Scientific Advisory; has grants pending with the National Institutes of Health, the Alzheimer Association, the Department of Defense, and the American Health Assistance Foundation; and has received funding for expenses unrelated to the activities listed from the Alzheimer Association, the National Institutes of Health, Beeson Scientific, Japan Geriatrics Society, Wake Forest University, and the State of California Department of Human Services. Dr Laffan reported that she received salary support and was reimbursed for travel to professional society meetings from the National Institutes of Health. Dr Redline reported that her institution received a California Pacific Medical Center subcontract via a National Institutes of Health grant; she is a board member for the American Academy of Sleep Medicine; her institution has received an endowment for a professorship in sleep medicine from Dr Peter Farrell, CEO of RosMed Inc; and has multiple grants pending with the National Institutes of Health on sleep apnea. Dr Spira reported that he has received honoraria as a clinical editor for the International Journal of Sleep and Wakefulness—Primary Care, which receives pharmaceutical industry support. Dr Ancoli-Israel reported that she is a consultant for Johnson & Johnson, Merck, Purdue Pharma LP, sanofi-aventis, and Pfizer and has grants pending with the National Institutes of Health. No other disclosures were reported.
Funding/Support: The Study of Osteoporotic Fractures is supported by funding from the National Institutes of Health. The National Institute on Aging provided support for this study under grants AG05407, AR35582, AG05394, AR35584, AR35583, R01 AG005407, R01 AG027576-22, 2 R01 AG005394-22A1, and 2 R01 AG027574-22A1, AG05407, AR35582, AG05394, AR35584, AR35583, AG026720. In addition, this study was supported by National Institute on Aging grant AG026720. Dr Yaffe is supported in part by National Institute on Aging grant K24AG031155. Dr Spira is supported by a Mentored Research Scientist Development Award (NIA 1K01AG033195). Dr Ancoli-Israel is supported by National Institute on Aging grant AG08415.
Role of the Sponsor: The National Institute on Aging did not play a role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.