Sleep-disordered breathing has been associated with declines in memory, attention, and executive functions in both middle-aged adults and children, with intermittent hypoxemia and fragmented sleep patterns being the factors most frequently associated with decline.1 In elderly patients, some studies have found a relationship between cognitive impairment and sleep-disordered breathing,2,3 while others have not.4,5 However, conflicting results may be explained by methodological differences across these studies that assessed longitudinal data in elderly individuals,2 cross-sectional data from young and elderly individuals3 or only elderly individuals,5 or direct comparisons between younger and older patients.4 Most importantly, cross-sectional studies do not allow conclusions to be drawn regarding causality. Because sleep-disordered breathing is common among older adults and effective treatments for sleep-disordered breathing exist, establishing the possible prospective association between sleep-disordered breathing and cognitive functioning in elderly individuals is important at both theoretical and practical levels. The article by Yaffe et al6 in this issue of JAMA helps to clarify this association.
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Purchase Online Access to this article for 24 hours
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 4
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
and access these and other features:
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.