We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Lab Reports |

Fat Stem Cells

Tracy Hampton, PhD
JAMA. 2011;306(5):480. doi:10.1001/jama.2011.1088.
Text Size: A A A
Published online


Scientists conducting studies in mice have found a way to identify the progenitors of cells that make up fat tissue (Daquinag AC et al. Cell Stem Cell. 2011;9[1]:74-86). These fat stem cells—adipose stromal cells (ASCs)—are responsible for driving fat expansion that can lead to obesity.

Researchers at the University of Texas Health Science Center at Houston isolated a peptide that specifically homes to ASCs and used it to purify the corresponding ASC surface receptor. They found this to be a fragment of decorin, a protein regulating cell adhesion, proliferation, and migration. A search for proteins that bind to this fragment led them to resistin, a protein secreted by fat cells and a key regulator of metabolism, for which the receptor has been unknown.


stem cells

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles
Isolation and characterization of human islet stellate cells. Exp Cell Res Published online Nov 4, 2015;
Cell Therapy for Intracranial Aneurysms: A Review. World Neurosurg Published online Nov 4, 2015;