Author Contributions: Drs Bray and Smith had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Drs Bray and Smith contributed equally to this work.
Study concept and design: Bray, Smith, de Jonge, Rood, Most.
Acquisition of data: Bray, Smith, de Jonge, Rood, Martin, Most, Brock, Mancuso.
Analysis and interpretation of data: Bray, Smith, de Jonge, Xie, Rood, Martin, Redman.
Drafting of the manuscript: Bray, Smith, de Jonge, Xie, Brock, Mancuso, Redman.
Critical revision of the manuscript for important intellectual content: Bray, Rood, Martin, Most, Redman.
Statistical analysis: Bray, Smith, Xie, Redman.
Obtained funding: Bray.
Administrative, technical or material support: Bray, Smith, de Jonge, Rood, Martin, Most.
Study supervision: Bray, Smith, de Jonge.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Bray reported that he has been a consultant to Abbott Laboratories and Takeda Global Research Institute; is an advisor to Medifast, Herbalife, and Global Direction in Medicine; and has received royalties for the Handbook of Obesity. Dr Martin reported that he is a consultant to Bristol-Myers Squibb, Eli Lilly, Elcelyx, Merck, and Philips; has received compensation from International Life Sciences Institute for manuscript preparation; and has been reimbursed for travel expenses from Catapult Health, Domain & Associates, and the University of Tennessee. No other author reported disclosures.
Funding/Support: This study was supported in part by the US Department of Agriculture grant 2010-34323-21052 and by funding from Louisiana State University.
Role of the Sponsors: The US Department of Agriculture and Louisiana State University had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; or preparation, review, or approval of the manuscript.
Online-Only Material: The Author Video Interview is available here.
Additional Contributions: We thank all of the volunteers without whose active participation there would not have been a study. The diligence of the clinical and dietary staff were essential for the smooth functioning of this study, and we appreciate their work. We thank Eric Ravussin, PhD, Claude Bouchard, PhD, and Donna Ryan, MD (all with Pennington Biomedical Research Center, Louisiana State University) for their helpful comments during the preparation of the manuscript. None of these persons were compensated for their contributions.
This article was corrected for errors on February 21, 2012.