In Reply: Dr Bush and Dr Handsfield are both
concerned about the generalizability of our results. We offer 4 observations
First, our stratified probability sample was designed to be representative
of English-speaking adults aged 18 to 35 years in Baltimore, Md. We oversampled
segments of the population with higher rates of sexually transmitted diseases
(STDs) (ie, young black men, whites living in census tracts with high rates
of reported STDs). Oversampling is routinely used in household surveys to
ensure adequate sample sizes for difficult-to-survey or numerically rare segments
of the population.1,2 The
resulting prevalence estimates are not biased by the oversampling and remain
generalizable to English-speaking Baltimore adults aged 18 to 35 years because
sample weights account for the oversampling in the statistical analysis. Our
population-based sample provides one of the first estimations of the prevalence
of gonococcal and chlamydial infection in a general population.
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