0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Letters |

Hormone Replacement Therapy and Risk of Breast Cancer—Reply

Emily White, PhD; Chi-Ling Chen, PhD
JAMA. 2002;287(18):2360-2361. doi:10.1001/jama.287.18.2359.
Text Size: A A A
Published online

Extract

In Reply: Dr Grant is concerned that OCs and short-term HRT may increase the risk of breast cancer. In our study, there was no association of OC use with breast cancer risk (Table 1), and no association of HRT use of up to 18 months' duration (Table 2). Therefore, we believe that it was appropriate to include both OC users who did not use HRT and users of HRT for less than 3 months in the reference group of non-HRT users.

We appreciate Dr Stadel's concern that the association of HRT with breast cancer appeared to be stronger for women with surgical menopause than for women who had natural menopause. We did not highlight those differences because based on a statistical test for interaction, those apparently large group differences were consistent with chance. On inspection, the trend across the HRT use groups is similar (ie, using the <18-month HRT group as the reference) for the 2 menopause categories. Thus, the difference is due to variability between the 2 reference groups (nonusers of HRT with natural vs surgical menopause).

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 3

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();