In Reply: Dr Grant is concerned that OCs and
short-term HRT may increase the risk of breast cancer. In our study, there
was no association of OC use with breast cancer risk (Table 1), and no association
of HRT use of up to 18 months' duration (Table 2). Therefore, we believe that
it was appropriate to include both OC users who did not use HRT and users
of HRT for less than 3 months in the reference group of non-HRT users.
We appreciate Dr Stadel's concern that the association of HRT with breast
cancer appeared to be stronger for women with surgical menopause than for
women who had natural menopause. We did not highlight those differences because
based on a statistical test for interaction, those apparently large group
differences were consistent with chance. On inspection, the trend across the
HRT use groups is similar (ie, using the <18-month HRT group as the reference)
for the 2 menopause categories. Thus, the difference is due to variability
between the 2 reference groups (nonusers of HRT with natural vs surgical menopause).
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 3
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.