To The Editor: Dr Chen and colleagues1 reported that recent long-term HRT was associated
with an increased risk of breast cancer, and that such HRT was related particularly
to lobular tumors.
Table 1 of their article shows that 30.8% of the cases and 32.4% of
the controls had histories of surgical menopause, and for these women Table
3 shows that oral HRT within the past 5 years was associated with a significant
increase in the risk of breast cancer across durations of HRT ranging from
less than 18 months (odds ratio [OR], 1.75) to more than 57 months (OR, 2.45; P = .003 for trend). For women with histories of natural
menopause, however, Table 3 shows less evidence of an increase in the risk
of breast cancer across durations of oral HRT ranging from less than 18 months
(OR, 0.92) to more than 57 months (OR, 1.41; P =
.10 for trend).
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 3
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.