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Letters |

Relationship Between Apolipoprotein E ∊4 and Sleep-Disordered Breathing at Different Ages

Daniel J. Foley, MS; Kamal Masaki, MD; Lon White, MD, MPH; Susan Redline, MD, MPH
JAMA. 2001;286(12):1447-1448. doi:10.1001/jama.286.12.1447.
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To the Editor: Dr Kadotani and colleagues1 reported an association between apolipoprotein E ∊4 (which is coded by the ApoE4 allele) and sleep-disordered breathing (SDB) in a study of 791 adults, aged 32 to 68 years, in Wisconsin. We examined this association among 718 Japanese-American men, aged 79 to 97 years, who were evaluated for SDB as part of a recent follow-up examination of participants in the Honolulu-Asia Aging Study of dementia that began in 1991 (previously unpublished data).


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