To the Editor: In their analysis of a large
and contradictory literature on the developmental effects of prenatal cocaine
exposure, Dr Frank and colleagues1 concluded
that, "After controlling for confounders, there was no consistent negative
association between prenatal cocaine exposure . . . " and a number of developmental
outcomes. Although the authors carefully qualified that they were assessing
unique effects of cocaine in comparison with those of multiple other risk
factors, one concern is that this review will be interpreted as indicating
that there are no negative effects of prenatal cocaine exposure.
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