To the Editor: Dr Shelton and colleagues1 do not provide the actual data on which their conclusions
are based. The Hamilton depression (HAM-D) scores are presented only as unadjusted
group means. As HAM-D scores 20 and higher were required for trial entry,
the subgroup analysis of "less severely depressed" subjects (HAM-D score <
22) could only include subjects with a HAM-D score of 20 or 21. It is arbitrary
to designate an individual with a score of 21 as less severely depressed than
a score of 22. Similarly, the authors state that the mean (SD) duration of
current major depressive disorder was 2.3 (6.3) years in the treated group
and 2.7 (5.6) years in the placebo group. The SDs show that the distribution
is dramatically skewed, perhaps to an extent as to possibly affect the statistical
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Purchase Online Access to this article for 24 hours
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 2
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
and access these and other features:
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.