To the Editor: Dr Shelton and colleagues1 conducted an 8-week intervention trial comparing
St John's wort extract with placebo for the treatment of major depression.
Ironically, their study was limited by the same criticisms they leveled against
previous studies of St John's wort—a flawed protocol and inappropriately
generalized findings. Shelton et al concluded that the herbal extract was
not effective for treatment of major depression, but their trial did not include
a prescription antidepressant arm to indicate whether the study was sensitive
enough to detect effectiveness.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 2
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.