0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Letters |

Breast Cancer in Women With HIV/AIDS—Reply

Morten Frisch, MD, PhD; Robert J. Biggar, MD; Eric A. Engels, MD, MPH; James J. Goedert, MD
JAMA. 2001;285(24):3090-3091. doi:10.1001/jama.285.24.3090.
Text Size: A A A
Published online

Extract

In Reply: As we noted in our article, the negative trend was not accompanied by an overall deficit of breast cancer cases. The 143 breast cancers in our study occurring from 60 months before to 27 months after AIDS onset in the cohort of 302 834 men and women with HIV infection and AIDS corresponded closely to the expected number (n = 135.3) based on incidence rates for the general population (RR, 1.1; 95% confidence interval [CI], 0.9-1.2).

It is difficult to judge whether 2 cases of breast cancer in a group of 2460 HIV-positive individuals treated at the Beth Israel Deaconess Medical Center is more or less than one should expect. This expected number depends strongly on the sex, age, and race composition of this group and on the observation time these individuals were at risk of breast cancer. However, assuming that their patients were similar to our cohort in terms of sex (16.2% female), age, race, and duration of observation, the expected number of breast cancer cases would only be 1.1 ([2460 × 135.3] ÷ 302 834). Even if one third of the cohort that was followed up by Drs Pantanowitz and Dezube was female, the expected number of breast cancer cases (again assuming an age and race composition and a mean follow-up similar to that of ours) would be 2.3, and the corresponding RR would not be significantly reduced (RR, 0.9; 95% CI, 0.1-3.1).

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();