In Reply: Our statement that "1 million infants are born each year with heart defects" referred to a worldwide estimate rather than one limited to the United States.1- 3 However, we appreciate this opportunity to discuss further the incidence of congenital heart disease.
The annual rate of pregnancy in the United States is estimated to be between 5 million and 6 million by the National Center for Health Statistics of the Centers for Disease Control and Prevention. This includes an estimated 4 million live births and nearly 1 million spontaneous abortions or stillbirths.4 Congenital cardiac defects are recognized in approximately 0.5% to 1.25% of live births.3,4
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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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