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Letters |

Utility of Endoscopic Screening for Upper Gastrointestinal Adenocarcinoma

Jesper Lagergren, MD; Weimim Ye, MD; Reinhold Bergström, PhD; Olof Nyrén, MD, PhD
JAMA. 2000;284(8):961-962. doi:10.1001/jama.284.8.956.
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To the Editor: The incidence of esophageal and gastric cardia adenocarcinoma is increasing in Western Europe and the United States.1 Survival rates2 are substantially improved by early tumor detection.3 Therefore, it seems important to identify high-risk persons in whom endoscopic surveillance might be warranted. Recently, symptomatic reflux4 and obesity5 were found to be strong independent risk factors for these tumors, particularly for esophageal adenocarcinoma.4,5 Endoscopic surveillance of persons with reflux has been suggested,6 but the benefits and efforts are unknown.

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