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November 24, 1999, Vol 282, No. 20 >

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Letters | November 24, 1999

The Crisis in Clinical Research—Reply

Kenneth Shine, MD
JAMA. 1999;282(20):1913-1916. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-20-jbk1124.
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In Reply: The importance of maintaining opportunities for physician-scientists to perform laboratory-based, disease-oriented research is appropriately identified by Dr Rockey. The pressures on them persist. However, the medical science training programs leading to the MD-PhD have been important training grounds for laboratory-based, disease-oriented physicians. At least until recently, similar programs for disease-oriented clinical investigators were not available. Hopefully, the significant increases in the overall NIH budget will improve the funding levels for PhD, MD-PhD, and MD scientists conducting laboratory-based research. The recent NIH initiatives in clinical research offer real opportunities for complementing these efforts with stronger programs for clinical investigators, including physician-scientists doing clinical research.

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