To the Editor: The Seychelles Child Development
Study is a longitudinal study of the effects of prenatal and postnatal exposure
to methylmercury from fish consumption on children's development.1 A cohort of 740 mother-infant pairs was enrolled
at 6 months of age and examined with age-appropriate developmental tests at
6, 19, 29, and 66 months. Exposure was measured with total mercury concentration
in maternal hair during pregnancy and in children's hair at 66 months. Associations
between prenatal and postnatal (66-month analyses only) exposure and developmental
outcomes were examined with multiple regression analyses, adjusted for covariates.
No adverse effects have been found through the 66-month evaluations.1
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