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Letters | May 5, 1999

Intensive vs Clinical Follow-up After Treatment of Primary Breast Cancer: 10-Year Update of a Randomized Trial

Domenico Palli, MD; Antonio Russo, MD; Calogero Saieva, MD; Stefano Ciatto, MD; Marco Rosselli Del Turco, MD; Vito Distante, MD; Paolo Pacini, MD;

JAMA. 1999;281(17):1586. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-17-jbk0505.

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To the Editor: Two randomized trials performed in Italy¹^- 2 failed to show any impact of intensive diagnostic follow-up on 5-year mortality for patients with primary breast cancer. We have now evaluated the mortality at 10 years in 1 of these large trials, designed to compare the effectiveness of 2 alternative follow-up protocols (intensive vs clinical) offered to study participants during the first 5 years after the treatment of primary breast cancer.

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Figure. Overall 10-Year Kaplan-Meier Survival Curves by Group for 1243 Breast Cancer Patients Randomized to Intensive Diagnosis or Routine Clinical Follow-up

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Palli D, Russo A, Saieva C, et al. Intensive vs Clinical Follow-up After Treatment of Primary Breast Cancer: 10-Year Update of a Randomized Trial. JAMA. 1999;281(17):1586. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-17-jbk0505.

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Intensive vs Clinical Follow-up After Treatment of Primary Breast Cancer: 10-Year Update of a Randomized Trial

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Figure. Overall 10-Year Kaplan-Meier Survival Curves by Group for 1243 Breast Cancer Patients Randomized to Intensive Diagnosis or Routine Clinical Follow-up

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