Author Contributions: Dr Kesselheim had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Kesselheim, Misono, Shrank.
Acquisition of data: Kesselheim, Misono, Lee, Shrank.
Analysis and interpretation of data: Kesselheim, Misono, Stedman, Brookhart, Choudhry, Shrank.
Drafting of the manuscript: Kesselheim, Misono, Lee, Shrank.
Critical revision of the manuscript for important intellectual content: Kesselheim, Misono, Stedman, Brookhart, Choudhry, Shrank.
Statistical analysis: Stedman, Brookhart, Choudhry.
Obtained funding: Kesselheim, Shrank.
Administrative, technical, or material support: Kesselheim, Misono, Lee, Shrank.
Study supervision: Kesselheim, Shrank.
Financial Disclosures: None reported.
Funding/Support: The study was supported in part by a grant from the Attorney General Prescriber and Consumer Education Grant Program. Dr Kesselheim's work was supported by an Agency for Healthcare Research and Quality Post-Doctoral Fellowship in Health Services Research at the Harvard School of Public Health. Dr Brookhart is supported by a career development award from the National Institute on Aging (AG027400). Dr Shrank is supported by a career development award from the National Heart, Lung, and Blood Institute (K23HL090505-01).
Role of the Sponsor: These funding organizations had no role in the design and conduct of the study; in the collection, management, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: Paul Shekelle, MD, PhD (Veterans Affairs Greater Los Angeles Health Care System and RAND Corp), provided comments on an earlier version of the manuscript. Jerry Avorn, MD (Brigham and Women’s Hospital and Harvard Medical School), helped conceive the study and provided comments on the design and manuscript. Neither received compensation.