Published Online: March 29, 2014. doi:10.1001/jama.2014.2630.
Study concept and design: Muntner, Cushman, Goff, G. Howard, Levitan, Safford.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Muntner.
Critical revision of the manuscript for important intellectual content: Colantonio, Cushman, Goff, G. Howard, V. Howard, Kissela, Levitan, Lloyd-Jones, Safford.
Statistical analysis: Muntner, Colantonio, Levitan.
Obtained funding: Cushman, V. Howard, Kissela, Safford.
Administrative, technical, or material support: Cushman, G. Howard, V. Howard, Lloyd-Jones, Safford.
Study supervision: Muntner, G. Howard, V. Howard, Safford.
Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Muntner reported receiving grants and personal fees from Amgen Inc outside the submitted work. Dr Cushman reported receiving grants from diaDexus outside the submitted work. Dr Levitan reported receiving grants from Amgen Inc outside the submitted work. No other disclosures were reported.
Funding/Support: This research project is supported by a cooperative agreement U01 NS041588 from the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Services. Additional support was provided by grants R01 HL080477 and K24 HL111154 from the National Heart, Lung, and Blood Institute.
Role of the Sponsor: Representatives of the National Institutes of Health have been involved in the review of the manuscript but not directly involved in the collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Neurological Disorders and Stroke or the National Institutes of Health.
Additional Information: Drs Goff and Lloyd-Jones served as co-chairs of the 2013 American College of Cardiology/American Heart Association Guideline on the Assessment of Cardiovascular Risk.
Additional Contributions: We thank the other investigators, the staff, and the participants of the REGARDS study for their valuable contributions. A full list of participating REGARDS investigators and institutions and further information about the study can be found at http://www.regardsstudy.org.