Published Online: May 20, 2013. doi:10.1001/jama.2013.5124
Author Contributions: Dr Doig had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Doig, Simpson.
Acquisition of data: Doig, Simpson, Sweetman, Finfer, Heighes, Davies.
Analysis and interpretation of data: Doig, Simpson, Sweetman, Finfer, Cooper, Davies, Solano, Peake.
Drafting of the manuscript: Doig.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Doig.
Obtained funding: Doig, Simpson, Finfer, Cooper.
Administrative, technical, or material support: Doig, Simpson, Sweetman, Heighes.
Study supervision: Doig, Simpson, Sweetman, Heighes.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Doig reported receiving academic research grants from Fresenius Kabi Deutschland and Baxter Healthcare; consulting fees from Nestle Nutrition, Fresenius Kabi Deutschland, and Baxter Healthcare; speakers' honoraria from Nestle Nutrition, Baxter Healthcare, and Fresenius Kabi Deutschland; and travel support from Fresenius Kabi Deutschland, Baxter Healthcare, and Nestle Nutrition. Ms Simpson reported receiving academic research grants from Fresenius Kabi Deutschland and Baxter Healthcare, speakers' honoraria from Fresenius Kabi, and travel support from Fresenius Kabi Deutschland and Baxter Healthcare. Dr Solano reported receiving consulting fees from Pfizer and Astra and conference attendance support from Pfizer. Dr Finfer reported receiving academic research grants from Fresenius Kabi Deutschland and Fresenius Kabi Australia and consultancy fees from Esai and Eli Lilly. Ms Heighes reported receiving academic research grants and travel support from Fresenius Kabi Deutschland and Baxter Healthcare. Dr O’Leary reported receiving speakers' honoraria from Baxter Healthcare. Ms Sweetman reported receiving academic research grants from Fresenius Kabi Deutschland and Baxter Healthcare. No other disclosures were reported.
Funding/Support: This work was supported by a peer-reviewed academic grant from the Australian National Health and Medical Research Council (NH&MRC) and unrestricted academic grants from Fresenius Kabi Deutschland and Baxter Healthcare. Fresenius Kabi Australia supplied the study parenteral nutrition.
Role of the Sponsor: As a peer review funding body, the NH&MRC provided constructive comments on the study design. Fresenius Kabi Deutschland, Fresenius Kabi Australia, and Baxter Healthcare had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript. Although participating sites were compensated for the costs of conducting the trial, site investigators did not receive financial compensation for their contributions.
Early PN Trial Contributing Sites and Site Investigators, alphabetical by site:Auckland City Hospital, New Zealand: Jodi Brown, Heidi Buhr, Vicki Cochrane, Michelle Eccleston, Eileen Gilder, Shay McGuiness, Rachael Parke, Anna Whitley. Austin Hospital, Victoria, Australia: Rinaldo Bellomo, Glenn Eastwood, Donna Goldsmith, Inga Mercer, Kim O’Sullivan, Leah Peck, Helen Young. Bendigo Hospital, Victoria: Catherine Boschert, John Edington, Jason Fletcher, Gary Koch, Mainak Majumdar, Tracey Shard, Julie Smith. Blacktown Hospital, New South Wales, Australia: Kalpesh Gandhi, Kiran Nand, Treena Sara. Box Hill Hospital, Victoria: David Charlesworth, Suzanne Eliott, David Ernest, Angela Hamilton (deceased), Belinda Howe, Inga Mercer, Sam Radford, Jaspreet Sidhu. Cabrini Hospital, Victoria: Jonathon Barrett, Felicity Hawker, MariaGrazia de Luca. Calvary Mater Hospital Newcastle, New South Wales: Irene Bailey, Jorge Brieva, Katrina Ellem. Campbelltown Hospital, New South Wales: Gillian Bishop, Olivia Mulligan, Ray Eckhardt. Concord Hospital, New South Wales: David Milliss, Helen Wong. Dandenong Hospital, Victoria: Subhash Arora, Michael Buist, Bridget O’Bree, Kate Shepherd, Susan Van Dyk. Frankston Hospital, Victoria: Sharon Allsop, Subhash Arora, John Botha, Himangsu Gangopadhyay, David Lewis, Naomi Pratt, Fiona Turnbull, Jodi Vuat. Geelong Hospital, Victoria: Allison Bone, Claire Cattigan, Tania Elderkin, Melissa Fraser, Anne Kilmonth, Neil Orford, Tania Salerno. Gold Coast Hospital, Queensland, Australia: Alan Spencer, Mandy Tallott, Rosemary Whitbread. Gosford Hospital, New South Wales: Rob Cameron, Sheridan Hatter, Jackie Hyslop, Peter Rye. John Flynn Private Hospital, Queensland: Robin Holland, Roslyn van der Vooren. John Hunter Hospital, New South Wales: Elise Crowfoot, Miranda Hardie, Peter Harrigan, Sam Jenkins. Liverpool Hospital, New South Wales: Deepak Bhonagiri, Sharon Micallef, Michael Parr. Lyell McEwin Hospital, South Australia, Australia: Rajaram Ramadoss, Josette Wood, Julie Zuppa. Middlemore Hospital, New Zealand: Marilyn Beggs, Peter Dzendrowskyj, Chantal Hogan, Judy Tai, Anna Tilsley, Tony Williams. Monash Medical Centre, Victoria: Jonathon Barrett, Sue Burton, Tim Crozier, Pauline Galt, Ainsley Gillies, Rebecca Ioannidis, Marnie Reilly, Carly Thornhill. Nepean Hospital, New South Wales: Cheryl Cuzner, Rebecca Gresham, Larissa Hoyling, Tony Maclean, Maria Nikas, Phoebe Palejs, Ian Seppelt, Leonie Weisbrodt, Sarah Whereat. Royal North Shore Hospital, New South Wales: Anthony Delaney, Gwen Hickey. Royal Hobart Hospital, Tasmania, Australia: David Cooper, Kathryn Marsden, Rick McAllister, Ram Sistla, Andrew Turner. St George Hospital, New South Wales: Vanessa Dhiacou, Deb Inskip, Theresa Jacques, Alina Jovanovska, Michael O’Leary, Rebecca Sidoli. St Vincent's Hospital Melbourne, Victoria: Nicole Groves, Jenny Holmes, John Santamaria, Roger Smith, Antony Tobin. St Vincent's Hospital Sydney, New South Wales, Australia: Jeff Breeding, Priya Nair, Claire Reynolds, Karen Storer. Sydney Adventist Hospital, New South Wales: Roger Harris, Linley Shields, Hui (Whay) Yang. The Prince of Wales Hospital, New South Wales: Frances Bass, Michelle Campbell, Pam Edhouse, Naomi Hammond, Maryam Sana, Yahya Shehabi, Victoria Stockdale, Barb Trytko. The Queen Elizabeth Hospital, South Australia : Catherine Kurenda, Sandra Peake, Patricia Williams. Wellington Hospital, New Zealand: Lynn Andrews, Dick Dinsdale, Peter Hicks, Diane Mackle. Wollongong Hospital, New South Wales: Michael Davis, Michelle Gales, Francisco Hill, Bronwyn Johnson, Adam Purdon, Martin Sterba, Renee Xu.