This population epidemiology study uses regional claims data from Germany to investigate associations between infections in the first 2 years of life and development of type 1 diabetes.
This randomized trial reports high rates of sustained virologic response in the first part of a open-label study of ombitasvir, paritaprevir (co-dosed with ritonavir), and dasabuvir with ribavirin for 63 patients with hepatitis C virus genotype 1 and human immunodeficiency virus 1 co-infection.
This study describes the development and diagnostic accuracy of a host-response RNA signature for distinguishing bacterial from viral infection in febrile children younger than 5 years.
This cluster randomized clinical trial compares the effects of behavioral interventions on rates of inappropriate (not guideline-concordant) antibiotic prescribing during ambulatory visits for acute respiratory tract infections.
This study describes the development and diagnostic accuracy of a host response RNA signature for distinguishing bacterial from nonbacterial infection in infants aged 60 days or younger.
This prospective study sought to determine the incidence, risk factors, and attributable mortality of ICU-acquired infections in patients admitted with or without sepsis.
This pharmacoepidemiology study estimates the rate of outpatient, oral antibiotic prescribing by age and diagnosis in the United States and the estimated portion of antibiotic use that may be inappropriate in adults and children.
This Viewpoint explains the importance of optimized antibiotic use in controlling the increasing rate of illness, mortality, and morbidity resulting from antibiotic-resistant infections.
A cross-sectional study of 1-day prevalence surveys conducted in 183 US acute care hospitals in 10 states found that antimicrobial drugs were used was 49.9% of the time and use of broad-spectrum drugs was common.