The US Burden of Disease Collaborators used a systematic analysis of descriptive epidemiology of diseases and injuries, their sequelae, and risk factors or clusters of risk factors from 1990 to 2010 to describe the health status of the United States. In an editorial, Fineberg discusses the health of the US population.
This randomized trial reports that, among overweight and obese participants with type 2 diabetes, use of daily liraglutide, a glucagon-like peptide 1 analog, resulted in weight loss over 56 weeks compared with placebo.
In a retrospective cohort study of veterans with diabetes initially treated with metformin, Roumie and coauthors compared time to acute myocardial infarction, stroke, or death in patients who added insulin or a sulfonylurea.
This meta-analysis of trials comparing treatments for obstructive sleep apnea investigates associations between continuous positive airway pressure vs mandibular advancement devices and change in blood pressure.
In a double-blind randomized clinical trial of 2159 infants with HLA-conferred disease susceptibility and a first-degree relative with type 1 diabetes, The TRIGR Study Group tests the hypothesis that weaning to an extensively hydrolyzed formula decreases the cumulative incidence of diabetes-associated autoantibodies, May 2002-April 2013 at 78 study centers in 15 countries.
This study uses Framingham cohort data to assess whether the 2013 American College of Cardiology/American Heart Association guidelines for cholesterol management improve identification of adults at higher risk of cardiovascular events compared with the 2004 Adult Treatment Panel III guidelines.
This narrative review summarizes current thinking about the diagnosis and treatment of distal symmetric polyneuropathy.
This Review summarizes advances in diagnosis and treatment of type 1 and type 2 diabetes between 2005 and 2015.
Using a complex, multistage, probability sampling design, Xu and coauthors conducted a cross-sectional survey in a nationally representative sample of 98 658 Chinese adults at least 18 years old in 2010 to investigate the prevalence of diabetes and glycemic control in the Chinese adult population.