Marrouche and coauthors report the results of the DECAAF study, which was a multicenter assessment of the association of atrial tissue fibrosis identified by delayed enhancement magnetic resonance imaging (MRI) and catheter ablation outcomes in patients with atrial fibrillation.
This randomized trial reports that the addition of metformin to insulin does not improve glycemic control in overweight adolescents with type 1 diabetes and increases incidence of gastrointestinal adverse events.
This case series involving children and young adults with cancer whose genomic sequencing results were the basis for clinical case recommendations charaterizes the number of clinically actionable findings and resulting patient outcomes.
Lee and coauthors report on initial clinical indications for clinical exome sequencing referrals and molecular diagnostic rates for different indications and for different test types.
This case series describes the diagnostic yield of whole-exome sequencing (molecular autopsy) performed postmortem on patients younger than 45 years who died unexpectedly.