This Medical News feature examines mindfulness meditation as a nonpharmacologic approach to managing chronic pain.
This retrospective study compared risk of death among Medicaid patients in Tennessee initiating long-acting opioid therapy for chronic noncancer pain with patients taking anticonvulsants or cyclic antidepressants.
This guideline from the Centers for Disease Control and Prevention makes 12 recommendations to improve communication about opioids for chronic pain, to improve the safety and effectiveness of pain treatment, and to reduce risks associated with long-term opioid therapy.
This cohort study compares changes in physical function and pain among obese patients 1 to 3 years after bariatric surgery (Roux-en-Y gastric bypass or laparoscopic adjustable gastric banding).
This randomized trial compares the effects of mindfulness-based stress reduction vs cognitive behavioral therapy vs usual treatment for improving symptoms and physical function among adult patients with chronic lower back pain.
This randomized trial evaluates the use of vitamin D supplementation vs placebo in treating knee pain and preventing tibial cartilage loss among patients with symptomatic knee osteoarthritis.
This Clinical Evidence Synopsis summarizes a Cochrane review on the efficacy of topical nonsteroidal anti-inflammatory drugs to treat musculoskeletal conditions, such as sprains, strains, and contusions.
This 2×2 factorial randomized trial compares the effects of larger vs smaller chest tube size and nonsteroidal anti-inflammatory drugs vs opiates on pain and efficacy of pleurodesis in patients with malignant pleural effusion.
This narrative review summarizes current thinking about the diagnosis and treatment of distal symmetric polyneuropathy.
This JAMA Clinical Evidence Synopsis discusses treatments that are associated with improved outcomes for women with endometriosis.
This Viewpoint discusses how the Institute of Medicine stands behind the estimate that 100 million Americans have chronic pain and the committee’s recommendation that better data are needed to create the cultural transformation required to reduce the effects of pain in America.
This randomized trial reports measures of pain and function among patients with chronic knee pain who underwent needle acupuncture, laser acupuncture, or sham or no acupuncture.
Yawn and coauthors summarize a 2014 evidence-based report on the management of sickle cell disease. In an accompanying Editorial, DeBaun discusses the challenge of creating an evidence-based guideline for sickle cell disease.