This Clinical Evidence Synopsis summarizes a Cochrane review of clinical trials comparing the effects of long-term colchicine treatment with usual care or placebo on cardiovascular events in patients with hepatobiliary diseases, pericarditis, or other diseases.
This study uses risk scores from 2 studies to assess their accuracy in predicting cardiovascular events among patients with stable coronary heart disease.
This secondary analysis of data from the Dual Antiplatelet Therapy (DAPT) trial describes development of a risk prediction tool to identify benefits and harms of continuing thienopyridine therapy after an initial year of treatment following percutaneous coronary intervention.
This population-based study assessed the prevalence of myocardial scarring, of which the majority were undetected by electrocardiography or clinical evaluation.
This Rational Clinical Examination examines the accuracy of initial history, physical examination, electrocardiogram, and risk scores combined with the first cardiac-specific troponin for diagnosing acute coronary syndrome in the emergency department.
This randomized trial reports that among men with coronary heart disease, use of a lifestyle-focused text messaging service vs usual care resulted in modest improvement in low-density lipoprotein cholesterol levels and greater improvement in other cardiovascular disease risk factors.
This study uses individual participant data from the Emerging Risk Factors Collaboration to estimate reductions in life expectancy associated with cardiometabolic multimorbidity.
This Viewpoint discusses potental hazards related to the concomitant use of nonsteroidal anti-inflammatory drugs and antithrombotic therapy after myocardial infarction.
This analysis of data from Danish administrative registries reports that among patients receiving antithrombotic therapy after myocardial infarction, use of nonsteroidal anti-inflammatory drugs was associated with increased risk of bleeding and thrombotic events.
Ikeda and coauthors determine whether daily, low-dose aspirin reduces the incidence of cardiovascular (CV) events compared with no aspirin in older Japanese patients with multiple atherosclerotic risk factors.
This retrospective pooled analysis of 8 clinical trials reports that obstructive non–infarct-related artery disease was common among patients presenting with ST-elevation myocardial infarction (STEMI).
This randomized clinical trial of 4524 patients undergoing transfemoral coronary angiography reports that vascular closure devices were noninferior to manual compression in terms of vascular access-site complications and reduced time to hemostasis.
This retrospective cohort study of US veterans undergoing elective coronary angiography reports that nonobstructive coronary artery disease (CAD), compared with no apparent CAD, was associated with a significantly greater 1-year risk of myocardial infarction and all-cause mortality.